Topic: somatosensory stimulation

Developing a technology able to measure in-vivo and non-invasively the electrical activity of the human spinal cord would fulfill an important and still unmet need in both basic and clinical research. In this work, we describe a novel recording and analysis pipeline to obtain non-invasive, high-resolution images of the electrical activity of the spinal cord in humans (Electrical Spinal Imaging, ESI). Using this approach, we provide a detailed description and physiological characterization of the spatiotemporal dynamics of the peripheral, spinal and cortical activity elicited by somatosensory s

Cross-modal recruitment of visual cortical areas by auditory and somatosensory stimulation have often been reported in early blind humans. However, lower resting-state functional connectivity (rsFC) between visual and somatosensory and auditory cortical areas and weaker interhemispheric rsFC have been reported in blind humans. Moreover, rsFC is more variable in blind individuals than in sighted controls. Cross-modal recruitment of visual cortical areas has also been shown in mice. Cross-modal activation involves modifications of the excitatory/inhibitory balance, rather than establishing new c

Neuronal oscillations can be used to understand brain plasticity phenomena during trauma. The oscillations of local field potentials (LFP) represent the phasing of the membrane potentials of different types of neurons at both the cortical and subcortical levels. In this project, we have studied the plasticity process that occurs in the primary visual cortex following monocular enucleation in mice using LFP recordings. To elicit a response in V1, animals are subjected to protocols of visual, auditory, and somatosensory stimulation while the electrode remains in the same location (figure). We ha