Topic: sound-evoked activity

Adaptive myelination is the emerging concept of tuning axonal conduction velocity to the activity within specific neural circuits over time. Sound processing circuits process signals with microsecond precision: a time scale that is amenable to adjustment in length and thickness of myelin. Sound-evoked responses during postnatal development increase the activity of auditory axons and enhance myelin thickness, while sensory deprivation prevents such radial growth during development. Deprivation occurring during adulthood reduces myelin thickness. However, it is unclear if sensory stimulation adj

Integration of information across different senses is a common property of cortical neurons. Somatosensory input impacts on auditory cortical processing through a mechanism that suppresses sound-evoked activity (Lohse et al., 2021). We carried out a number of experiments to investigate a) the perceptual implications of this crossmodal integrative process and b) its context dependence. In order to assess whether somatosensory suppression of sound-evoked activity affected the ability of mice to detect acoustic stimuli, we first performed a near-threshold sound detection experiment. While simulta