“Understanding the Function and Dynamics of Organelles through Imaging”
Jennifer Lippincott-Schwartz · Janelia Research Campus, Howard Hughes Medical Institute
Tue, Nov 17, 2020 · 05:45 UTC
Powerful new ways to image the internal structures and complex dynamics of cells are revolutionizing cell biology and bio-medical research. In this talk, I will focus on how emerging fluorescent technologies are increasing spatio-temporal resolution dramatically, permitting simultaneous multispectral imaging of multiple cellular components. In addition, results will be discussed from whole cell milling using Focused Ion Beam Electron Microscopy (FIB-SEM), which reconstructs the entire cell volume at 4 voxel resolution. Using these tools, it is now possible to begin constructing an “organelle i