Spinal circuits

Spinal circuits are essential for movement automaticity. The spinal cord not only executes and adjusts motor outputs by integrating information from multiple somatosensory channels but also undergoes lasting adaptation following repetitive practice in various motor tasks, even without brain inputs. However, the spinal mechanisms underlying these lasting sensorimotor adjustments remain unclear. Here, we establish a quantitative kinematic framework to characterize a spinal conditioning behavior, where spinal circuits, functionally isolated from the brain, learn to adapt motor output and retain t

Henrik Lindén discusses spinal circuits that generate rhythmic movement and the models used to understand their activity.