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Topic: stable connectivity matrices

ePoster
1 ePoster

In Applied Mathematics and Biology

ePoster · Computational Neuroscience

The space of high-dimensional Dalean, amplifying networks and the trade-off between stability and amplification

Nicoleta Condruz, Chaitanya Chintaluri, Ivan Bulygin, Tim Vogels · Bernstein Conference 2024

Cortical neurons exhibit rich, time-dependent patterns of activity that are often selective to specific stimuli. From a dynamical systems perspective, such complex activity can be conceptualized as ON/OFF responses, or also as transient amplification. It is still unclear if transient amplification is an artifact of a carefully tuned model, or an intrinsically occurring phenomenon. Moreover, minute changes in the connectivity of amplifying networks can cause catastrophic dynamic instabilities. How biological circuits could settle into stable, yet amplifying connectivity regimes in an ever-chang