Compare eukaryotic genomes to investigate evolutionary change and biological differences. Hands-on workflows span read quality and assembly, gene and repeat annotation, completeness assessment and visualization. Participants detect sequence and structural variation, compare synteny, infer orthology and explore gene loss and functional annotation, linking technical choices to evolutionary interpretation. Short- and long-read approaches are covered, with cloud computing and introductory Linux support. 2027-02-15–2027-02-19, 14:00–20:00 daily, Europe/Berlin (CET, UTC+01:00). Online course; fee €
Clio Karageorgiou discusses structural variation and the research brought together in a Heredity special issue. The episode provides a focused introduction to changes in genome structure and their importance for understanding genetic diversity.