Synapse

The functioning of a synapse depends on its accessibility to proteins and, thus, on the localization of protein sources along the dendrite (Westenbroek 2009, Vacher et al. 2008). Therefore, the behaviour of the synapse highly depends on the availability of proteins and ion channels and any perturbation in the localization and availability of these components would lead to a dysfunction of the synapse. Hence, understanding the localization and distribution of ion channels and proteins in the dendrite in relation to the synapse is crucial. Using super-resolution microscopy, Helm et al., 2021 der

The cellular processes underlying the formation of memory share many similarities with the immune system, as both are intricate networks that affect, and are affected, by the body via multiple ‘modes’ of operation. Indeed, the two systems are functionally integrated, with the brain’s immune system helping to regulate synaptic plasticity and memory. At the molecular level, memory and the immune system are functionally integrated by non-coding RNAs (ncRNAs), which have recently emerged as key regulators of cellular activity throughout the phases of memory and in the adaptive immune system. Given

…Brains Become Who We Are”—the brain’s synapses—are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrat