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Modulation of sensory deficits in Shank3b mice through cathodal tDCS

Manuel Ambrosone, Elena Montagni, Francesco Saverio Pavone, Anna Letizia Allegra Mascaro · FENS Forum 2024

Autism Spectrum Disorders (ASD) are a range of neurodevelopmental disorders, characterized by behavioral and neuronal anomalies. Phelan-McDermid Syndrome (PMS) constitutes a specific neurodevelopmental disorder exhibiting ASD-like behaviors, caused by mutations or deletions of SHANK3 gene. Mice lacking the SHANK3 gene are widely considered a reliable model to study PMS, since they show autism-like behaviors and sensory deficits, such as aberrant whisker-dependent texture discrimination and local hyperactivation of the barrel-field cortex. These local alterations mirror dysfunctions of the enti

ePoster · Neuroscience

…Direct Current Stimulation (tDCS) targeting the ventromedial PFC (vmPFC) to understand whether this brain region occupies a crucial role in sustaining metacognition. A randomized, double-blind, within-subjects research design was u

ePoster · Cognition

…direct current stimulation (tDCS) over the left prefrontal cortex in improving the clinical outcome of traditional treatment in adolescents with AN. Fifty girls with AN (aged 10 to 18 years) underwent 18 sessions of tDCS treatment (active or placebo) over the PFC (an

ePoster · Neuroscience

How to combine brain stimulation with neuroimaging: "Concurrent tES-fMRI

Charlotte Stag, Lucia Li, Axel Thielscher et al. · University of Oxford, University of Imperial College London, ...

…direct current stimulation (tACS and tDCS), are non-invasive brain stimulation technologies increasingly used for modulation of targeted neural and cognitive processes. Integration of tES with human functional magnetic resonance imaging (fMRI) provides a novel avenue in human brain mapping for investigating the neural mechanisms underlying tES. Advances in the field of tES-fMRI can be hampered by the methodological variability between studies that confounds comparability/replicability. To address the t

Thu, Feb 4, 2021 · 04:00 UTC

Seminar · Brain Imaging