Topic: temporal cortex

Alzheimer’s disease (AD) is a neurodegenerative disorder with complex pathological manifestations and is the leading cause of cognitive decline and dementia in elderly individuals. A major goal in AD research is to identify new therapeutic pathways by studying the molecular and cellular changes in the disease, either downstream or upstream of the pathological hallmarks. In this study, we present a comprehensive investigation of cellular heterogeneity from temporal cortex region of 40 individuals, comprising healthy donors and individuals with differing tau and amyloid burden. Using single-nucl

Cochlear implants (CIs) are neural prostheses that enable severely hearing-impaired to understand speech. However, outcome is highly variable and multimodal training strategies including haptic stimulation might contribute to this aim. Given that the temporal cortex has been shown to be necessary for vibrotactile temporal discrimination, we aimed to investigate the impact of hearing loss and restoration on vibrotactile perception in adults.Therefore, we conducted a 32-channel EEG during a passive perception task and two oddball tasks using a standard stimulus (250 Hz, 100 ms) and a target with