Temporal precision

…work includes greater spatial or temporal precision, closed-loop control and multi-site stimulation, with proof-of-concept hardware or software development. Clinical trials are not allowed. Support is up to USD 275,000 in direct costs over two years, with a USD 200,000 annual limit. The next new-application deadline is 16 October 2026 at 5 p.m. in the applicant organisation’s local time.

Synaptic integration is crucial for inter-neuronal communication, and excitatory-inhibitory integration is utterly important in lateral superior olive (LSO) neurons, enabling sound localization. For this purpose, LSO neurons integrate excitatory inputs from the ipsilateral cochlear nucleus (CN) with inhibitory inputs from the medial nucleus of the trapezoid body (MNTB). The strength and number of excitatory and inhibitory inputs show notable differences. The convergence of multiple excitatory input fibers (~10‑40) is a source for synaptic noise in the spike driving inputs. We focused on how sy