Threat responses

…learning and memory, stress and threat responses, brain-body interactions, medial prefrontal function and behavioural strategies for interpreting neural dynamics. Additional sessions explore hippocampal computation, orbitofrontal contributions to learning and decisions, endogenous opioids, retrosplenial cortex, and activity-dependent plasticity in sensory pathways. Morning and evening symposia leave time for informal scientific discussion. Attendance is capped below 100. R

…that support survival, motivation, threat responses and pain. Topics include neural heterogeneity, protein-related timescales, nervous-system evolution and the limits of focusing exclusively on spikes and cortex. She also describes efforts to make automated behavioural labels consistent across experiments.

Fear learning and extinction are crucial for survival and lead to disease, if impaired. Recently, it has been demonstrated that the cerebellum is bidirectionally controlling fear learning via the fastigial nucleus (FN) to ventrolateral periaqueductal grey (vlPAG) pathway in rodents (Frontera et al., 2020, Lawrenson et al., 2022). The mechanisms of the cerebellar influence on fear learning still need to be elucidated. Using a combined anterograde/retrograde viral tracing strategy, we targeted a dorsal raphe nuclei (DRN)/vlPAG pathway that projects on the FN. In extracellular recordings during a