Topic: total synthesis

Join Jonathan George’s group on a Leverhulme-funded, three-year project investigating biomimetic synthesis of complex natural products, particularly meroterpenoids. The work develops cascade reactions using dearomatisation, rearrangement and cycloaddition, linking total synthesis to reaction discovery and mechanistic analysis. It includes synthesis, purification, structural characterisation and collaboration with computational chemists and researchers in biosynthesis and natural products. The annual salary is GBP 37,369–45,641. Applicants can develop conference, publication, mentoring and labo

Jennifer Newton and Jamie Durrani discuss the future of total synthesis and the development of halogen-bond catalysis. The episode examines how funding pressures and changing priorities affect a long-established synthetic discipline, then introduces the origins and possible applications of an emerging catalytic approach.