Topic: two-layer network

In many brain regions, the stimulus tuning of neurons is stable on a timescale of hours but not on a timescale of weeks, a phenomenon often called ‘representational drift’. For example, in piriform cortex, which is commonly considered primary olfactory cortex, the cells responsive to a given odor are completely uncorrelated with those activated by the same odor two weeks later (Schoonover et al., 2021). This would seem to imply that piriform cortex, like other brain regions whose activity appears to drift, is useless for the retrieval of associative memories learned several weeks prior. Howeve

Adaptation is ubiquitous in sensory systems. Sensory neurons change their activity depending on the past stimulus history, which they integrate at various timescales. Short- and long-term adaptations have been mostly studied using simple, artificial stimuli, but rarely with natural scenes. Even at the level of the retina, it is unclear how these adaptive processes impact ganglion cells, the retinal output, and how they change their feature selectivity to natural scenes as a function of the recent stimulus history. This raises a major challenge for our understanding of how ganglion cells proce