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Topic: ventral CA1

ePoster
4 ePosters

In Neuroscience

A role for hippocampal CA1 in structural learning in mice

Svenja Nierwetberg, Andrew Macaskill, David Orme · COSYNE 2023

Learning relationships between cues in our environment enables us to recognise common underlying structures of events and is thought to form the basis of episodic memory. This type of learning - often called relational or structural learning - requires retaining the identity of a stimulus as well as its relation to other cues, for example its position in time or location in space. One area implicated in structural learning is the hippocampus. Specifically, neurons in the CA1 area of the hippocampus have been shown to represent variables essential for constructing a relational structure of the

Sat, Mar 11, 2023

ePoster · Neuroscience

A role for hippocampal CA1 in structural learning in mice

Svenja Nierwetberg, David Orme, Andrew F. MacAskill · COSYNE 2025

The meaning of individual events or cues in the environment is often dependent on their position relative to other cues surrounding them. The ability to learn about relationships between such ambiguous cues – often called structural learning – enables us to recognise common underlying structures of events and is thought to form the basis of episodic memory. One area implicated in structural learning is the hippocampus. Specifically, neurons in the CA1 area of the hippocampus have been shown to represent variables such as cue configurations and their order in space and time. To investigate the

ePoster · Neuroscience

Oxygen in motion: Anxiety-related changes in oxygen levels within the ventral hippocampus of rats

Zoi Balla, Patrizia Voehringer, Andreas Johann Genewsky, Carsten Wotjak · FENS Forum 2024

The ventral hippocampus has emerged as a central hub for the orchestration of negative effects. We employed wireless amperometric O2 measurements in freely moving rats as a surrogate readout for changes in neuronal activity with translational value for fMRI studies in humans. From the Research Domain Criteria (RDoC) matrix, here, mainly one branch, namely the negative valence system is addressed using a modified Elevated Plus-Maze, male Wistar rats are tested under controllable (modified Elevated T-Maze, mETM with free exploration of one open and two closed arms) and uncontrollable (Open Arm C

ePoster · Neuroscience

A role for hippocampal CA1 in structural learning in mice

Svenja Nierwetberg, David Orme, Andrew F. MacAskill · FENS Forum 2024

The meaning of individual events or cues in the environment is often dependent on their position relative to other cues surrounding them. The ability to learn about relationships between such ambiguous cues – often called structural learning – enables us to recognise common underlying structures of events and is thought to form the basis of episodic memory. One area implicated in structural learning is the hippocampus. Specifically, neurons in the CA1 area of the hippocampus have been shown to represent variables such as cue configurations and their order in space and time. To investigate the

ePoster · Neuroscience