ePoster · Neuroscience
Julie Vidal, Kévin Rachita, Anaïs Servais, Patrice Péran, Jérémie Pariente, Fabrice Bonneville, Jean-François Albucher, Lola Danet, Emmanuel Barbeau · FENS Forum 2024
The interthalamic adhesion (IA) is a structure that connects the median borders of both thalami across the third ventricle. Given that it is difficult to identify on routine neuroimaging, its anatomical variants and function remain poorly studied. The objective of this study was to clarify the role of the IA on cognition. The study comprised 42 healthy subjects and a cohort of 40 patients with isolated thalamic strokes at the chronic stage. All participants underwent 3T research T1w and FLAIR MRI as well as a neuropsychological assessment. The presence, absence, type of anatomical variant, and
ePoster · Neuroscience
Sathwik Prathapagiri, Jesus S. Garcia-Salinas, Jaromir Dolezal, Pavel Daniel, Martin Kojan, Lena Jurkovicova, Robert Roman, Cadgas Topcu, Wojciech Fortuna, Monika Sluzewska, Milan Brazdil, Pawel Tabakow, Gregory Worrell, Jan Cimbalnik, Michal Kucewicz · FENS Forum 2024
High-frequency oscillations (HFOs) have commonly been associated with the pathophysiology of epilepsy but recent evidence points to a cognitive role of neural activities in the gamma, ripple and fast ripple frequency bands (60-500Hz). In particular, encoding and recall of memory induces bursts of HFOs at distinct frequency and latency depending on the cortical location. How these local neural assembly activities are globally coordinated across the brain during memory processing remains elusive. Intracranial local field potential recordings from epilepsy patients were used to detect individual
ePoster · Neuroscience
Jan Cimbalnik, Jaromir Dolezal, Pavel Daniel, Martin Kojan, Lena Jurkovicova, Robert Roman, Wladyslaw Sredniawa, Wojciech Fortuna, Monika Sluzewska, Katarzyna Smarzewska, Peter Reinacher, Artur Weiser, Tymoteusz Skok, Tomasz Piernicki, Aleksandra Orzol, Amanda Lier, Sahar Seifzadeh, Marina Galanina, Bozena Kostek, Andrzej Czyzewski, Pawel Tabakow, Milan Brazdil, Michal Kucewicz · FENS Forum 2024
Intracranial human brain recordings from multiple stereotactically implanted depth electrodes using stereo-EEG (sEEG) technology for seizure localization provides unique local field potential signals (LFP) sampled with standard macro- and special micro-electrode contacts. Over one hundred macro- and micro-contact LFP signals localized in particular brain regions were recorded from each sEEG monitoring case as patients engaged in an automated battery of verbal memory and non-verbal gaze movement tasks. Subject eye and vocal responses in both visual and auditory task versions were automatically
ePoster · Neuroscience
Maria Renke, Aleksandra Frączek, Sahar Seifzadeh, Nastaran Hamedi, Jaromir Dolezal, Gregory Worrell, Jan Cimbalnik, Michał Kucewicz · FENS Forum 2024
Eye–tracking tasks engage both smooth pursuit and saccadic gaze movements. Performance of these different types of gaze movement during simple visual tasks, can indicate deficits in memory and executive functions. Similarly, changes in pupillary reflexes have been shown to reflect mental effort and cognitive processes. We hypothesised these non-invasive eye-tracking signals will predict verbal memory performance in patients with drug-resistant epilepsy.Twenty-nine patients completed simple eye-tracking tasks, probing Smooth Pursuit (SP) and Anti-Pro-Saccade (AP) gaze movements, and were groupe
ePoster · Neuroscience
Marina Galanina, Kucewicz Michal Tomasz, Jesus Salvador Garcia-Salinas, Sathwik Prathapagiri, Nastaran Hamedi, Maria Renke · FENS Forum 2024
The prevalence of memory deficits among epilepsy patients is approximately 50%, reported as a major factor affecting the quality of life. In particular, individuals with temporal lobe epilepsy are increasingly identified with a deficit termed Accelerated Long-Term Forgetting. Monitoring and treatment of these deficits require efficient automated tools for repeated probing of memory functions with or without concurrent recording of the brain activities. We used a classic verbal memory free recall paradigm, in which subjects recall out-loud words after a distractor, assessing performance by tran