Topic: visual areas

Episodic memory performance decreases with advancing age. According to theoretical models, such memory decline might be a consequence of age-related reductions in the ability to form distinct neural representations of our past. In this talk, I want to present our new age-comparative fMRI study investigating age-related neural dedifferentiation across different representational levels. By combining univariate analyses and searchlight pattern similarity analyses, we found that older adults show reduced category selective processing in higher visual areas, less specific item representations in oc

Information in the nervous system is encoded by the spiking patterns of large populations of neurons. The analysis of such high-dimensional data is typically restricted to simple, arbitrarily defined features like spike rates, which discards information in the temporal structure of spike trains. Here, we use a recently developed method called SpikeShip based on optimal transport theory, which captures information from all the relative spike-timing relations among neurons. We compared spike-rate and spike-timing codes in neural ensembles from six visual areas during natural video presentations.

It is appealing to disclose the state of an animal as well as the functional connectivity of its neuronal circuit by calculating pairwise and higher-order interactions (HOI) among neuronal activity. Here, we present a systematic approach to achieve these goals by analysing the spiking activity of simultaneously recorded neurons. To this end, we first developed a method to extract significant pairwise and triple-wise interactions among neurons. Using statistically significant data, we then analysed pairwise and HOI from large-scale spiking activities in visual areas of mice during natural movie