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Topic: visual exploration

ePoster
3 ePosters

In Neuroscience

ePoster · Neuroscience

Eye movement abnormalities as early biomarkers of Alzheimer’s disease

Andrea Zangrossi, Stefano Mozzetta, Valentina Carlucci, Giovanni Zorzi, Cinzia Bussè, Anna Chiara Cagnin, Maurizio Corbetta · FENS Forum 2024

The diagnosis of Alzheimer's disease (AD) typically occurs after the onset of cognitive symptoms. Consequently, the global challenge around the world is to identify early and easily accessible biomarkers. Intriguingly, certain brainstem structures, such as the Superior Colliculus (SC), which plays a pivotal role in fixation maintenance and saccade programming, exhibit neurofibrillary changes sooner than cortical regions (Uematsu et al., 2018) and is susceptible to tau pathology and neuronal loss in AD patients. Accordingly, eye movement abnormalities associated with AD are often observed durin

ePoster · Neuroscience

Revisitation during visual exploration linked to memory durability and hippocampal dynamics

Luise Graichen, Jozsef Arato, Isabella C. Wagner · FENS Forum 2024

Humans use eye movements to sample the visual world, and these impact which information is retained in memory. However, memory is not only affected by the amount of time spent viewing a visual scene but also by specific gaze patterns during visual exploration. Revisitations occur when the eye gaze returns to a previously fixated location, resembling retrieval processes and offering another chance to encode. What remains unclear is whether revisitations actually enhance long-term memory formation and how they are associated with hippocampal activity dynamics. In this study, 50 human participant

ePoster · Neuroscience

Spontaneous EEG correlates of visual exploration phenotypes: A replication study

Miriam Celli, Andrea Zangrossi, Ilaria Mazzonetto, Luca Lorenzon, Maurizio Corbetta · FENS Forum 2024

Eye movements are known to be driven by stimulus features (e.g., saliency). However, spatiotemporal dynamics of eye movements are remarkably stable within an individual. In a previous study, we recorded eye movements from 120 participants in a free-viewing task. Three principal components explained 60% of the variance of the data. The first principal component (PC1) loaded on fixation duration, and subjects could be clustered in two different visual exploration phenotypes: “static” and “dynamic” viewers. In a second EEG resting-state study on the same sample, carried out one year later, static