Topic: wake-sleep cycle

Brain information processing is shaped by fluctuations in neuronal rhythmic activities, each defining distinctive brain states. Switches in brain states during wake-sleep cycle are described at the network level, by a neuronal population shift from active to oscillatory state. At the cellular level, neurons switch from tonic to burst. This switch is organized thanks to neuromodulators. They refer to signaling molecules that induce reversible changes in functional properties of neurons or synapses. Simultaneously, learning and memory are attributed to the ability of neurons to modify their conn

The different behavioral states inherent to the wake-sleep cycle are reflected in the electrical activity of the cerebral cortex. Slow-wave sleep (SWS) and deep anesthesia are dominated by high amplitude slow-wave oscillations (SWO, < 1 Hz). With the increase in arousal, desynchronization and low-amplitude fast rhythms arise. While SWS and wakefulness dynamics have been comprehensively described, their transition remains relatively unexplored. Tort-Colet et al (2021) previously reported the emergence of an intermediate brain state, the microarousal brain state, characterized by the rhythmic