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Topic: XGBoost

ePoster
2 ePosters

In Neuroscience

Investigating behavioral variables underlying helping behavior in mice

Anna Agafonova, Leon Marquardt, Moises dos Santos Correa, Pavol Bauer, Sanja Mikulovic · FENS Forum 2024

In our previous study, we conducted a rescue behavior experiment. In this experiment, mice were trained to rescue a distressed familiar conspecific of the same sex by opening a door under two conditions: when the trapped mouse was in a dry or flooded chamber. We demonstrated that mice exhibit rescue behavior towards a distressed conspecific. Additionally, we discovered that inhibiting the dorsal hippocampus impairs this behavior. However, several questions regarding the specific components of impaired behavior remain. Does the emotional arousal of potential helpers increase when witnessing a d

ePoster · Neuroscience

The neurometabolic underpinnings of social rank – underlying mechanisms in the astrocytes of the nucleus accumbens

Silvie Ruigrok, Doğukan Ülgen, Thomas Larrieu, Marie-Isabelle Guillot de Suduiraut, Jocelyn Grosse, Cristina Cudalbu, Carmen Sandi · FENS Forum 2024

Social status is key to mental health and well-being. The nucleus accumbens (NAc) regulates motivated behaviors, including the establishment of social hierarchies. Our recent work underscored NAc mitochondrial energy metabolism as critical for social competition among rodents. However, the exact neurochemical and molecular underpinnings of the differences in NAc energy metabolism and the specific contribution of distinct cell types are yet to be determined. Magnetic resonance spectroscopy (MRS) allows the study of metabolites related to energy metabolism, neurotransmission, and cellular integr

ePoster · Neuroscience