27 results
Develop a quantitative single-molecule imaging platform for drug discovery with Steven F. Lee. The initial focus is alpha-synuclein aggregation in Parkinson’s disease. Responsibilities include assay development, higher-throughput compound screening, image-analysis pipelines and coordination with academic and commercial partners. The role also contributes to…
The MPI-PKS Visitors Program offers research appointments lasting from several weeks to two years, joining institute research groups, working independently, or forming temporary groups around a specific problem. Its Biological Physics division studies physical principles in biological systems and welcomes theoretical or computational physicists with a…
The Microenvironments for Medicine Group at IBEC seeks a PhD student to develop in vitro models of the oesophageal epithelium and investigate the role of cell and matrix mechanics in cancer initiation. The position is funded by a project of the Fundación Científica Asociación Española Contra el Cáncer and is developed in collaboration with Dr Albert Herms…
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Assistant Project Scientist in the structural biology of microtubule motors and regulatory proteins. The researcher will develop experiments and analyses involving molecular biology, biochemical reconstitution, cryo-electron microscopy sample preparation and imaging, single-particle structure determination using Relion and Cryosparc, and molecular model…
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Tenure-track appointment in theoretical biophysics, developing an independent research programme that complements the existing biophysics group. The anticipated start is August 1, 2027 in Montréal. Responsibilities include securing external research funding, undergraduate and graduate teaching, mentoring and departmental service. A relevant PhD and evidence…
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The Institute of Fundamental Technological Research, Polish Academy of Sciences (IPPT PAN) in Warsaw is recruiting a postdoc/assistant professor for an NCN OPUS 29 project led by Dr hab. Adolfo Poma. DNA bends, twists, opens and wraps around proteins, and RNA folds into hairpins, junctions and G-quadruplexes; these conformational changes control how genetic…
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Postdoctoral Flatiron Research Fellowship bridging the Biophysical Modeling group led by Michael Shelley and the Genomics group led by Olga Troyanskaya in the Center for Computational Biology. The joint project builds hybrid models that combine deep learning for genome interpretation with mechanistic biophysical representations of genome structure, dynamics…
The Optical Investigation of Dynamical Systems research unit, established at IIT in 2026 by Eli Slenders with an ERC Starting Grant, develops optical microscopy systems for measuring molecular diffusion and biomechanical properties in biological systems, including custom-built microscopes, control software and quantitative analysis pipelines for dynamic…
Investigate living systems using theoretical physics and experimental biology. Topics include cellular development, evolution, chromatin and collective behaviour away from equilibrium.
A January–June 2027 placement with the Biotherapeutics Discovery team in Cambridge, Massachusetts. Work focuses on evaluating and improving therapeutic antibodies and VHH candidates through binding, biophysical and cell-based assays. Activities include protein production and purification, mammalian cell culture, ELISA, Octet measurements, size-exclusion…
RIKEN’s Life and Medical Science Application Interface Platform Development Unit, led by Yasuhiro Matsunaga, seeks postdoctoral researchers for the TRIP-AGIS project. Research integrates biomolecular simulation with AI: agents that plan and execute reproducible simulation workflows; molecular-dynamics surrogates with physical-validity and…
Develop deep-learning methods for generative protein design at the interface of machine learning, molecular simulation, structural biology and experimental protein engineering. Projects can investigate conformational ensembles, integrate protein language models with physics, or design proteins for challenging membrane and sugar interfaces. The researcher…
Develop high-throughput methods to measure how protein interactions respond to mechanical force. The project combines protein engineering, yeast surface display, directed evolution, deep sequencing and single-molecule force measurements, with machine-learning models trained on the resulting data. Initial applications study interactions involved in blood…
Develop theory and computational methods for complex biomolecular systems in Helmut Grubmüller’s group. Topics include variational free-energy methods, solvation-shell thermodynamics, constant-pH simulations and Markovian thermodynamics, with applications to ribosomes, fatty-acid synthase, CRISPR systems and intrinsically disordered proteins. Doctoral…
Help establish Leif-Thore Deck’s new research group and investigate biomolecular phase transitions across scales. The work combines droplet microfluidics and fluorescence microscopy with thermodynamic and kinetic measurements of protein and peptide condensates, fibrils and crystals, connecting microscopic nucleation processes to litre-scale precipitation.…
Investigate cell fate and tissue morphogenesis in the Cell Science accelerator, aiming to make multicellular behaviour predictable and programmable. Develop mechanistic and quantitative research using model organisms or organoids, supported by advanced microscopy, cell and molecular engineering, and modelling expertise. Coordinate scientific projects and…
The goal of the Neural Dynamics accelerator is to understand how the brain generates flexible behavior. We aim to uncover the algorithms—implemented by dynamics in brain-wide neural circuits—that allow animals to build internal models, process information, and choose actions. We are searching for a Scientist to develop data-driven theories of how circuit…
Build scalable computational pipelines for biophysical models of neurons and neural populations. Apply machine learning and statistical inference to neural recordings, construct biologically realistic networks and help shape research directions at an early-stage company working at the intersection of neuroscience and computation. On-site engagement is…
Lead computational work on protein structure, design and antibody discovery. Develop methods that connect protein foundation models, antigen and binder datasets, biophysical prediction and experimental results, while building reliable data workflows and GPU-enabled tools. The position includes team leadership and collaboration with laboratory scientists.…
Develop biochemical and cellular assay strategies for drug-discovery programmes, connecting experimental pharmacology with AI-generated hypotheses. Responsibilities include target validation, screening cascades, functional assays and biophysical measurements, with emphasis on oncology and immunology. Lead external experimental work and collaborate across…
Develop theory for neuronal and metabolic activity in brain organoids, including sleep–wake behaviour, in the J. M. Schwarz Theory Group. Research connects physical learning and multiscale mechanics with experimental observations, collaborating with Orly Reiner and Yaakov Nahmias. The role includes student mentoring and an on-campus research presence. The…
Lead research linking focused ultrasound, synthetic biology and cancer immunotherapy in Nate Yoon’s RPBS Lab. Projects include ultrasound-responsive gene circuits, immune-cell mechanotransduction and acoustic tools for imaging and therapy. Mentor students and develop an independent research trajectory in an interdisciplinary engineering environment. The…
A full-time residential, NSF-funded appointment with Ethan Levien and Daniel Schultz, starting 1 January 2027 or earlier by agreement. Study antibiotic-driven phenotypic diversity in bacteria using stochastic models and experimental single-cell growth and gene-expression data. Laboratory work is not required. Optional teaching of one or two ten-week courses…
Independent theoretical-physics research within Cornell’s Laboratory of Atomic and Solid State Physics and the Kavli Institute. Topics span hard and soft condensed matter, cold atoms, quantum information, statistical physics, electronic structure, hydrodynamics and biophysics. Appointments are annual with an anticipated total duration of two years, an…