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Mathematical Modeling

Upcoming events

Seminar

Human balance: Delays, sensory dead zones and micro-chaos!

John G. Milton · The University of Texas at Austin

Tue, Oct 6 · 16:00 UTC · Online

How do humans stabilize an inverted pendulum, and why does a balanced pole eventually fall? Drawing on 25 years of fingertip pole-balancing research, this talk examines neural correction delays: longer poles move more slowly relative to the nervous system’s response time. Delay-differential models can stabilize the upright position, yet skilled people still experience falls. The proposed explanation is microchaos arising from interactions among delay, sensory dead zones and frequency-dependent force encoding. A region of transient falling solutions lies next to stable microchaotic dynamics. Such microchaos is absent in virtual frontal-plane balancing tasks, while models of standing postural sway lack the corresponding transient regime. The comparison suggests that human falls, unlike pole falls, are more plausibly associated with medical events or slips and trips.

comp-neuro+1
Seminar

Anderson Localization in Periodic Elastic Systems with Random Perturbations

Wei Wu · Jilin University, China

Fri, Oct 9 · 03:00 UTC · Online

This seminar investigates Anderson localization in subwavelength elastic periodic systems with random perturbations. For the unperturbed structure, layer-potential methods recast the eigenvalue problem as boundary integral equations, yielding asymptotic expressions for subwavelength eigenvalues and establishing a band gap above the subwavelength band. A Floquet transform then brings the perturbed problem into a periodic formulation and produces equations for resonant frequencies under general perturbations. Numerical experiments on monomer and dimer structures test agreement with the analysis. Increasing the strength and number of random perturbations demonstrates localization, providing a mathematical basis for elastic metamaterial design.

Anderson localization+2

SAB 2026 investigates the mechanisms that let natural and artificial agents adapt and survive in uncertain environments. Researchers compare biological behavior with robot experiments, computer simulations and mathematical models to evaluate principles and architectures of adaptive behavior. The programme covers collective intelligence, learning and skill acquisition, artificial perception and manipulation, and physical and social constraints on behavior. A cross-kingdom intelligence symposium includes Paco Calvo, Jens Krause, Vera Meyer and Ute Schmid. The meeting runs 19–22 October 2026 in Berlin, on CEST (Europe/Berlin, UTC+2). Workshops on 19 October at TU Berlin, Marchstraße 23, start at 09:00 following registration at 08:15; afternoon workshops end at 18:30. Topics include internal world models, genetic programming and homeostatic control. Conference sessions on 20–22 October take place at Universität der Künste, Georg-Neumann-Saal, Einsteinufer 43; sessions on 20 and 21 October begin at 09:00. Consult the detailed daily programme for session and venue changes. Public registration through Pretix is open. General admission is EUR 550, or EUR 450 for students with proof of status. Fees include sessions, coffee breaks and one networking dinner; lunches, other dinners and optional social activities are self-funded. No VAT is added.

Seminar

A prospective code for value in the serotonin system

Emerson Harkin · Max Planck Institute for Biological Cybernetics

Tue, Nov 10 · 17:00 UTC · Online

Why do dorsal raphe serotonin neurons respond to reward, surprise, salience and uncertainty in ways that resist a single explanation? This talk proposes that serotonin activity encodes prospective value: a prediction of cumulative future reward. The model is motivated by the unusually strong and persistent spike-frequency adaptation of these neurons, which may support efficient and accurate predictions. It reproduces important qualitative features of serotonergic responses that earlier models miss and predicts measured in vivo firing rates more accurately than competing accounts. By treating previously separate responses as manifestations of one prospective value code, the work connects serotonin physiology to its computational roles in learning and behaviour.

serotonin+2

Recordings

Seminar

Equilibrium Geometry and Chaotic Dynamics in Large Recurrent Neural Networks

Giancarlo La Camera · Stony Brook University

Wed, May 27 · 15:00 UTC

Large recurrent networks are important models in several fields, including neuroscience, machine learning, physics, and applied mathematics. Yet their dynamics are difficult to study directly, because high-dimensional nonlinear systems can exhibit rich behavior that is hard to summarize in terms of individual trajectories. In this talk, I will discuss an approach that seeks to understand such dynamics through the structure of the network’s equilibria. I will focus on a random balanced network of threshold-linear units that undergoes a transition from a single stable equilibrium to extensive chaos as the disorder strength crosses a critical value. Using a combination of Kac–Rice theory, replica calculations, numerical root-finding, and dynamical mean-field theory, we show that the chaotic regime contains an exponentially large number of equilibria. These equilibria are all saddles, but with only a fractionally small number of unstable directions. Surprisingly, despite the completely random connectivity, the equilibria are not scattered randomly through phase space. Instead, they are strongly correlated and confined to a comparatively small region. The chaotic attractor lies within this same region, suggesting a direct geometric link between the organization of unstable equilibria and the collective structure of the dynamics. This picture helps explain why networks with extensive chaos can nevertheless display dynamics dominated by a relatively small number of collective modes. More broadly, the results suggest that the geometry of equilibria provides a useful complementary perspective to dynamical mean-field theory for understanding high-dimensional neural dynamics. Presented in the van Vreeswijk Theoretical Neuroscience Seminar series (formerly WWTNS) on 2026-05-27. Recording duration: 00:46:40.

large recurrent neural networks+9

Open deadlines

Job

Theoretical Biology

Deadline Tue, Oct 13

Develop an analytical and computational research project with Arne Traulsen’s Department of Theoretical Biology. Possible directions include population structure, evolutionary game theory, microbial populations, ecological stochasticity, complex life cycles and infectious-disease models. The project will be developed with the incoming researcher to reflect their interests and skills. The institute’s working language is English. This vacancy belongs to the September 2026 Max Planck Postdoc Program call, which accepts applications until 13 October 2026 at 12:00 CEST through the official application platform.

Develop high-resolution air-quality models and correction algorithms suited to African conditions in a fully funded doctoral position at the African Research Centre on Air Quality & Climate, Mohammed VI Polytechnic University. The employer lists this opening in Ben Guerir and provides an application contact on its recruitment page.

Develop models of how cells sense and transmit mechanical cues, linking deformable soft materials and cell interfaces to intracellular signalling and mechanosensitive calcium responses. The project is primarily computational, with opportunities to connect models to experiments. Join Vesna Bacheva’s research at the Groningen Research Institute of Pharmacy, located within UMCG. Employment is full time for one year initially, with possible renewal for three further years. Applications close on 16 October 2026 at 23:59 Dutch local time.

This NIH BRAIN Initiative funding opportunity supports new or substantially advanced theories, mechanistic or predictive models, and computational or statistical methods that improve quantitative understanding of brain function across scales. Tools must address complex neural and behavioral data and be made broadly available to the neuroscience research community.

New and updated

Develop data-driven theories of how neural circuit structure shapes computation in the Allen Institute Neural Dynamics accelerator. The scientist will combine large-scale connectivity atlases, simultaneous recordings from thousands of neurons across brain regions, and targeted perturbations during behavior. Work includes mechanistic models fitted to connectivity and activity, coarse-grained descriptions of collective dynamics, analysis of which models remain compatible with data, and design of experiments that distinguish between them. The role involves close collaboration with anatomical, electrophysiological and imaging teams, and communicating research through publications and conferences. Based in Seattle, Washington, with most hours on site. The stated annual salary range is $87,450–$108,250. Relocation assistance is offered; work visa sponsorship may be available. Remote work, when permitted, must take place in Washington State.

Seminar

Deciphering the cortical output code – A multiscale approach to predictive brain modelling

Marcel Oberlaender · Dept. of Integrative Neurophysiology, Vrije Universiteit Amsterdam, Netherlands

Mon, Oct 5 · 07:30 UTC

The study tests whether cortex preserves information during sparse-to-dense coding by targeting thalamocortical synapses to dendritic calcium-spike initiation zones, enabling output neurons to multiplex information through a 1-2-3 action-potential syntax. Evidence across long-range pathways suggests that this anatomically and biophysically distinct dendritic nexus may provide a general mechanism for transforming sparse cortical representations into dense output streams.

AI-generated summary
cortical output code+9
Conference

SIAM Conference on Applications of Dynamical Systems (DS27)

Atlanta, United States

May 23–27, 2027

The Society for Industrial and Applied Mathematics convenes researchers developing and applying dynamical-systems methods across biology, chemistry, physics, climate science, social science, industry and data science. Themes include computational, experimental, theoretical and data-driven methods; AI-informed systems; fluid and climate dynamics; materials; networks; pattern formation; population dynamics; stochastic systems and tipping points. Minisymposium proposals are due 26 October 2026, followed by contributed lecture, poster and minisymposium-presentation abstracts on 23 November 2026.

SIAM’s computational science and engineering meeting covers mathematical models, scalable algorithms, scientific software, high-performance computing and scientific machine learning. It takes place in Pittsburgh on 22–26 February 2027. Travel-support applications are open until 30 November 2026. Abstract deadlines have passed; registration is scheduled to open in December 2026. The meeting is co-located with ACDA27 and the International Meshing Roundtable.

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