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Pilot and Feasibility Program
PILOT AND FEASIBILITY PROGRAM: PROJECT SUMMARY The goal of the Cedars-Sinai Digestive Diseases Research Center (CSDDRC) Pilot and Feasibility (P&F) Program is to provide monetary support, expertise, and technical support to advance innovative basic, translational, and clinical research that matches the overall goal and themes of the Center. The central theme of the CSDDRC is mechanisms and measurements of the fibroinflammatory response in gastrointestinal (GI) tissues, which reflects Center members’ research in three subthemes: 1) Gut Microbiome, 2) Gastrointestinal (GI) and Liver Metabolism, and 3) GI and Liver Injury. The mission of CSDDRC P&F Program is to support new investigators, established investigators who are new to digestive and liver disease research, and established digestive and liver disease investigators who want to start new or collaborative research that promises to lead to a paradigm shift in the digestive diseases field. In partnership with the Enrichment Program, we will provide guidance for P&F awardees in the form of mentorship and collaboration opportunities. The CSDDRC Biomedical Research Cores will also support P&F awardees, facilitating rapid progress of their new and collaborative digestive and liver disease research. The P&F Program’s outcome measures will include the number of high-impact research publications, grant applications, and subsequent extramural funding for P&F awardees. We will accomplish our goals through the following three specific aims. Aim 1 will solicit research proposals from P&F candidates whose proposed research aligns with the central theme and the subthemes of the CSDDRC. We will advertise P&F support widely across campuses, in addition to contacting department/institute directors to solicit their recommendations for promising young and established investigators who are interested in working in digestive and liver diseases. Aim 2 will select pilot project applications that meet CSDDRC P&F Program goals using rigorous review criteria. Each year, the P&F Program will select four pilot projects to be funded by the P30 grant and matched by institutional support. Submitted applications will be peer- reviewed and preliminarily scored based on the NIH review format by three local expert reviewers. Subsequently, after oral presentations by the P&F applicants, the External Advisory Board (EAB) members will undertake a second round of review, scoring, and discussion at the P&F Program Review meeting following the CSDDRC Annual Symposium. Funding decisions will be made during the P&F Program Review meeting. Aim 3 will assist P&F project investigators with career development and obtaining extramural funding for digestive disease research. P&F awardees will benefit from the Enrichment Program’s well-organized mentoring structure, led by experienced members of the CSDDRC, which includes the Grants-in-Progress Mentoring Program, Gastrointestinal Research-in-Progress meetings, and grant application workshops. P&F awardees will also be mentored through direct interactions with P&F Program Directors, Core Directors, members of the Internal Advisory Board and EAB, and individual or collaborative mentor teams.
Baby Toolbox Training and Certification Program
PROJECT SUMMARY Our objective is to improve early childhood outcomes and support the expansion of the NIH Infant and Toddler Toolbox (Baby Toolbox) by providing comprehensive training support to those interested in using it. The Baby Toolbox is a brand new, nationally-normed assessment for infants 1-42 months, commissioned by NICHD and released for public use in 2025. The Baby Toolbox is administered entirely on an iPad and includes 35 measures across six domains using novel technology (e.g., gaze tracking, automatic scoring, computerized adaptive testing). It has the potential to bring harmonization to the developmental fields, but in order for it to become a common currency for developmental research as envisioned, researchers need to know how to administer it and how to train others to administer it. We propose an education program that will include a week-long training workshop, certification activities, and post-workshop support to create expert cohorts of Baby Toolbox test administrators. Individuals who attend the workshops can become certified test trainers, capable of training others at their home institutions to administer the assessment thus creating a self-sufficient training model. Through the proposed educational program, we will provide funding to cover lodging, meals, and incidentals during the workshop, in addition to subsidizing transportation to/from the workshop and provide a one-year subscription to the Baby Toolbox. A portion of slots will also be set aside for those without current grant funding. Our team is highly qualified to complete these tasks because we have led the effort to develop the Baby Toolbox assessment and have already completed multiple training workshops for contract deliverables. This grant would continue the efforts started by the NICHD in funding the Baby Toolbox by helping support its rollout, implementation, and growth. To meet these goals, we have the following aims: Aim 1: Create cohorts of trained Baby Toolbox examiners who can catapult the Baby Toolbox into widespread use by hosting a comprehensive week-long education program (training workshop) yearly for individuals to learn how to administer and train others to administer the Baby Toolbox, Aim 2: Expand the use of the Baby Toolbox by recruiting and financially supporting individuals who will bring the Baby Toolbox into a variety of research and clinical settings. Aim 3: Build a virtual training resource of videos and materials to support ongoing fidelity checks with certified trainers, and future training efforts.
NeuroASCENT- Advancing Science through Career Enhancement and Neuroscience Training
The NeuroASCENT- Advancing Science through Career Enhancement and Neuroscience Training program will support neuroscience‑focused PhD students across multiple graduate programs by providing comprehensive scientific, professional, and research‑development training during their doctoral education. Strengthening the national neuroscience workforce requires ensuring that trainees have access to high‑quality research preparation, strong mentoring, and structured opportunities that enhance their scientific growth and career readiness. Recent analyses of U.S. doctoral recipients indicate that many talented trainees encounter barriers that limit full participation in research careers, underscoring the need for intentional support mechanisms that promote successful advancement. Over the last five years, CU Anschutz PhD programs have seen a substantial increase in students entering from a broad range of academic backgrounds. NeuroASCENT is designed to help these trainees progress efficiently by 1) promoting research excellence, 2) fostering leadership skills, 3) facilitating career development, and 4) providing individualized guidance. To achieve these goals, the program will provide career‑focused workshops, structured research externship opportunities, enhanced mentoring frameworks, and coordinated access to campus resources that extend beyond those offered by individual graduate programs. In partnership with the Office of Research Education, NeuroASCENT will complement and enhance the scientific training provided across biomedical PhD programs while offering added value to the broader CU Anschutz graduate community. Program Directors Dr. Quillinan and Dr. Hughes will oversee training activities, mentor matching, evaluation, program operations, and dissemination. An Institutional Advisory Board composed of research leaders will guide program oversight, and an External Advisory Board of graduate‑education experts will provide additional evaluation and strategic input. NeuroASCENT scholars will also serve on an Executive Advisory Board to develop leadership experience and contribute directly to program refinement. Trainees will typically enter the program after their second year of graduate training and will participate in activities focused on building a supportive peer/mentor network, strengthening scientific confidence and competence, and preparing for careers in academia, government, industry, or non‑profit research organizations.
Biostatistics, Ethics, Data Management, Research Design and Community Engagement(BEDRoC) Core
Biostatistics, Ethics, Data Management, Research Design and Community Engagement (BEDRoC) Core Abstract The Biostatistics, Ethics, Data Management, Research Design and Community Engagement (BEDRoC) Core will promote and support aging with serious illness science for the Center for Aging with Serious Illness (CASI). BEDRoC will provide expertise in statistical design and analysis, research ethics, and community engagement for all components of CASI. The Core's services will support the Research Project Leaders (RPLs) and Pilot Project Leaders (PPLs) and build capacity for the broader Dartmouth Health aging research community to conduct rigorous, impactful research to inform and improve care delivery for older adults with serious illness. BEDRoC includes expertise in mixed methods approaches that feature both quantitative and qualitative research methods to provide a comprehensive understanding of the complex issues related to aging with serious illness, ethical approaches to consent in research trials, multidimensional quality of life measurement, and innovative modeling approaches to studying clinical decision making. BEDRoC faculty have actively collaborated in study planning with each RPL, serving as both mentors and experienced collaborators on the three different projects involving decision aids for patients considering carotid revascularization, a patient-reported outcome-directed referral intervention to improve referral rates to palliative care services, and a pilot trial for a virtual/home-based exercise and a weight management osteoarthritis treatment program in older patients with osteoarthritis and multimorbidity. The BEDRoC Core will further support CASI by establishing an innovative training curriculum with workshops, tutorials, resources, and services, offered locally to RPLs and PPLs and extended to regional and national investigators in the IDeA network. In addition to their primary individual project mentors, each RPL will receive training and guidance from BEDRoC leaders through co-mentoring and RPL-focused works-in-progress sessions. BEDRoC will also provide access to a comprehensive inventory of patient-reported outcomes instruments, which are crucial in geriatric research to provide validated measures of health status, quality of life and functional ability outcomes. BEDRoC will coordinate with the Administrative and Mentoring Core to integrate community advisors in guiding their activities in support of the RPLs. BEDRoC will also enable research collaboration with and within the larger Dartmouth and IDeA investigator communities. The BEDRoC Core will build capacity for aging research and disseminate new resources to RPLs and PPLs, including innovative solutions created through robust community engagement. These services, resources, and solutions will ensure all projects operate in a cohesive, complementary, and collaborative manner to study approaches to improving the health of older patients with serious illness.
From Evidence to Scale: Implementation Science and Simulation Modeling to Transform HIV-Hypertension Care Integration
Project Summary As HIV programs mature, cardiovascular disease (CVD) is becoming a leading contributor to morbidity and mortality. Integration of HIV and CVD prevention, with a focus on hypertension–the most prevalent and impactful modifiable CVD risk factor, presents an opportunity to build more robust primary health systems that improve health outcomes and advance health system sustainability–a key priority for the U.S. PEPFAR program. Using an expanded version of the HIV Synthesis microsimulation model—which incorporates hypertension and CVD outcomes—and data from the NHLBI-funded HLB-SIMPLe consortium’s cluster randomized trials in six African countries, we will evaluate the health effects, cost-effectiveness, and scalability of implementation strategies to promote HIV-hypertension integration to improve health outcomes for people with and without HIV under a range of health system constraints. Our first aim is to develop and validate an additional layer to HIV Synthesis model that accounts for health system constraints and implementation strategies for integration of HIV and hypertension care. This will include parameterization using data from the WHO Health System Building Blocks framework and empiric data from trials in the HLB-SIMPLe consortium. Our second aim is to evaluate the health effects and cost-effectiveness of implementation strategies for HIV-hypertension integration to identify the most effective and scalable approaches for settings with varying health system constraints representative of conditions in west, east, and southern Africa. Analyses will include scenarios targeting people with HIV and scaling up to the broader population. Our third aim focuses on engaging policymakers and program managers to promote uptake of findings through dissemination workshops and interactive modeling tools, with tailored model outputs to specific health system contexts. Using qualitative interviews with policymakers, we will use the Weiss schema for conceptualizing research utilization to assess model impact on decision-making. We will use the Translational Science Benefits Model, to capture, classify and conceptualize the clinical, policy, economic, and operational impacts and identify barriers and facilitators to use in country programs focused on HIV, hypertension, and related NCDs. The overarching project goal is to inform evidence-based, cost-effective implementation strategies for integrating NCD care into HIV platforms, improving population health outcomes in Africa and advancing implementation science through generalizable knowledge about the intersection of implementation strategies, health system strength, and service integration.
Facilitating the Advancement of Research and Education for Undergraduate Students by Incorporating Laser Scanning Confocal Microscopy (FAREUS-LSCM)
PROJECT SUMMARY/ABSTRACT The University of Puerto Rico at Aguadilla (UPR-Aguadilla) requests funding to acquire a Nikon AX Galvo Confocal Laser Scanning Microscope (LSCM) with a TI2-E inverted platform and a four- laser configuration (405/488/561/640 nm) to establish transformative imaging capabilities at our resource-limited institution serving 96% Pell Grant recipients. This state-of-the-art instrument addresses a critical infrastructure gap, enabling high-resolution fluorescence imaging, live-cell microscopy, and quantitative analysis essential for competitive biomedical research and undergraduate education. The LSCM will directly support four active research projects spanning parasitology (monogenean host-specificity studies), plant pathology (coffee biocontrol development), environmental chemistry (metalloprotein biomarkers), and neuroscience (astrocyte dysfunction in diabetic epilepsy) while integrating into core laboratory courses including Immunology (BIOL 4009) and Undergraduate research courses (BIOL 3108 and QUIM 4999). Our multidisciplinary faculty, in partnership with the Neuroimaging and Electrophysiology Facility (NIEF) Excellence Imaging Center, offers expertise in confocal microscopy, encompassing advanced imaging and specialized sample preparation techniques. This collaboration ensures effective implementation of the technology, sustained technical support, and high-quality training programs that will enhance research productivity and broaden educational impact. The broad, long-term objective is to transform UPR-Aguadilla from a primarily teaching institution into a research-active campus capable of producing graduate-school-ready students equipped with cutting-edge technical skills. Access to advanced confocal microscopy will stimulate new research collaborations, enhance faculty productivity, and provide 30-40 students annually with hands-on experience in modern imaging technologies currently absent from our curriculum. The instrument will strengthen our partnership with the emerging Natural History Museum of Puerto Rico for specimen digitization and support comprehensive outreach programs targeting 25-50 high school students annually through "Seeing Science Up Close" workshops. Expected outcomes include 1- 2 peer-reviewed publications within three years, establishment of 1-2 new institutional collaborations, and measurable enhancement of biomedical research capacity. This investment will significantly advance STEM education and research opportunities at UPR-Aguadilla while expanding access to cutting-edge scientific instrumentation for students pursuing biomedical careers and contributing to the development of skilled researchers in the biomedical sciences.
COSYNE 2025
The COSYNE 2025 conference was held in Montreal with post-conference workshops in Mont-Tremblant, continuing to provide a premier forum for computational and systems neuroscience. Attendees exchanged cutting-edge research in a single-track main meeting and in-depth specialized workshops, reflecting Cosyne’s mission to understand how neural systems function.
Brain Connectivity Workshop
Founded in 2002, the Brain Connectivity Workshop (BCW) is an annual international meeting for in-depth discussions of all aspects of brain connectivity research. By bringing together experts in computational neuroscience, neuroscience methodology and experimental neuroscience, it aims to improve the understanding of the relationship between anatomical connectivity, brain dynamics and cognitive function. These workshops have a unique format, featuring only short presentations followed by intense discussion. This year’s workshop is co-organised by Wellcome, putting the spotlight on brain connectivity in mental health disorders. We look forward to having you join us for this exciting, thought-provoking and inclusive event.
Bernstein Student Workshop Series
The Bernstein Student Workshop Series is an initiative of the student members of the Bernstein Network. It provides a unique opportunity to enhance the technical exchange on a peer-to-peer basis. The series is motivated by the idea of bridging the gap between theoretical and experimental neuroscience by bringing together methodological expertise in the network. Unlike conventional workshops, a talented junior scientist will first give a tutorial about a specific theoretical or experimental technique, and then give a talk about their own research to demonstrate how the technique helps to address neuroscience questions. The workshop series is designed to cover a wide range of theoretical and experimental techniques and to elucidate how different techniques can be applied to answer different types of neuroscience questions. Combining the technical tutorial and the research talk, the workshop series aims to promote knowledge sharing in the community and enhance in-depth discussions among students from diverse backgrounds.
Bernstein Student Workshop Series
The Bernstein Student Workshop Series is an initiative of the student members of the Bernstein Network. It provides a unique opportunity to enhance the technical exchange on a peer-to-peer basis. The series is motivated by the idea of bridging the gap between theoretical and experimental neuroscience by bringing together methodological expertise in the network. Unlike conventional workshops, a talented junior scientist will first give a tutorial about a specific theoretical or experimental technique, and then give a talk about their own research to demonstrate how the technique helps to address neuroscience questions. The workshop series is designed to cover a wide range of theoretical and experimental techniques and to elucidate how different techniques can be applied to answer different types of neuroscience questions. Combining the technical tutorial and the research talk, the workshop series aims to promote knowledge sharing in the community and enhance in-depth discussions among students from diverse backgrounds.
Bernstein Student Workshop Series
The Bernstein Student Workshop Series is an initiative of the student members of the Bernstein Network. It provides a unique opportunity to enhance the technical exchange on a peer-to-peer basis. The series is motivated by the idea of bridging the gap between theoretical and experimental neuroscience by bringing together methodological expertise in the network. Unlike conventional workshops, a talented junior scientist will first give a tutorial about a specific theoretical or experimental technique, and then give a talk about their own research to demonstrate how the technique helps to address neuroscience questions. The workshop series is designed to cover a wide range of theoretical and experimental techniques and to elucidate how different techniques can be applied to answer different types of neuroscience questions. Combining the technical tutorial and the research talk, the workshop series aims to promote knowledge sharing in the community and enhance in-depth discussions among students from diverse backgrounds.
COSYNE 2023
The COSYNE 2023 conference provided an inclusive forum for exchanging experimental and theoretical approaches to problems in systems neuroscience, continuing the tradition of bringing together the computational neuroscience community. The main meeting was held in Montreal followed by post-conference workshops in Mont-Tremblant, fostering intensive discussions and collaboration.
The evolution and development of visual complexity: insights from stomatopod visual anatomy, physiology, behavior, and molecules
Bioluminescence, which is rare on land, is extremely common in the deep sea, being found in 80% of the animals living between 200 and 1000 m. These animals rely on bioluminescence for communication, feeding, and/or defense, so the generation and detection of light is essential to their survival. Our present knowledge of this phenomenon has been limited due to the difficulty in bringing up live deep-sea animals to the surface, and the lack of proper techniques needed to study this complex system. However, new genomic techniques are now available, and a team with extensive experience in deep-sea biology, vision, and genomics has been assembled to lead this project. This project is aimed to study three questions 1) What are the evolutionary patterns of different types of bioluminescence in deep-sea shrimp? 2) How are deep-sea organisms’ eyes adapted to detect bioluminescence? 3) Can bioluminescent organs (called photophores) detect light in addition to emitting light? Findings from this study will provide valuable insight into a complex system vital to communication, defense, camouflage, and species recognition. This study will bring monumental contributions to the fields of deep sea and evolutionary biology, and immediately improve our understanding of bioluminescence and light detection in the marine environment. In addition to scientific advancement, this project will reach K-college aged students through the development and dissemination of educational tools, a series of molecular and organismal-based workshops, museum exhibits, public seminars, and biodiversity initiatives.
COSYNE 2022
The annual Cosyne meeting provides an inclusive forum for the exchange of empirical and theoretical approaches to problems in systems neuroscience, in order to understand how neural systems function. The main meeting is single-track, with invited talks selected by the Executive Committee and additional talks and posters selected by the Program Committee based on submitted abstracts. The workshops feature in-depth discussion of current topics of interest in a small group setting.
Brainstorms Festival
The Brainstorms Festival is the No1 online neuroscience and AI event for scientists, businesses, investors and startups. Join and listen to talks from leading scientists, take part in interactive discussions, and network with the people driving neurotech and AI innovation globally. The festival provides a digital playground for visionaries with dozens of medical innovations, panel discussions, workshops, a hackathon, and a neuroethics panel discussion which is crucial topic for neurodiversity and disability rights. Register now and be part of our amazing crowd!
Brain Awareness Week by IIT Gandhinagar
The Brain Awareness Week by the Centre for Cognitive and Brain Sciences, IIT Gandhinagar spans across 7 days and invites you for a series of talks, panel discussions, competitions and workshops on topics ranging from 'Using songbirds to understand how the brain initiates movements' to 'Cognitive Science and UX in Game Design' by speakers from prestigious Indian and International institutes. Explore the marvels of the brain by joining us on 15th March. Free Registration.
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