Embryology ePosters

During mammalian neurodevelopment, the establishment of spatial and temporally appropriate gene expression programmes ensures the correct production of distinct neural and glial cell types. This process is partially regulated by the modification of chromatin structure by epigenetic complexes, including the Polycomb…

Layer 5 pyramidal neurons (L5 PNs) are a major cortical output. Their connectivity approximates a recurrent neural network (RNN), with the majority of inputs coming from other L5 PNs. These neurons may underlie anesthesia-induced unconsciousness, by restricting information output from cortex. Therefore, understanding…