Poster preview
ePoster
A NOVEL FMRI APPROACH FOR WHOLE-BRAIN AND VENTRAL REGION CONNECTIVITY MAPPING IN MICE
Tomokazu Tsurugizawaand 3 co-authors
National Institute of Advanced Industry and Science Technology (AIST)
FENS Forum 2026 (2026)
Barcelona, Spain
Board PS06-09PM-371
Presentation
Date TBA
Board: PS06-09PM-371
Event Information
Poster Board
PS06-09PM-371
Poster
View posterAbstract
Functional magnetic resonance imaging (fMRI) is an important tool for investigating functional networks from rodents to humans. However, the widely used fMRI with T2*-weighted imaging technique has the serious problem of signal lack in the amygdala in rodents. The zero-echo time (ZTE) sequence does not show the signal lack in the ventral brain regions, such as the amygdala and the entorhinal cortex, but it has not been applied to functional imaging in these regions. In this study we used the ZTE sequence to image the neuronal activity in the amygdala in mice. Resting state functional connectivity was investigated in awake mice. We identified not only the typical functional connectivity such as the default mode network but also the functional connectivity including the amygdala. We also investigated neuronal activation in the whole brain following the noxious stimulation of the hind paw. The injection of formalin into the hind paw evoked early and latent signal increase in the pain-associated regions including the amygdala. These results suggest that ZTE sequence is useful to investigate the whole brain functional network including ventral regions.
Recommended posters
WHOLE-BRAIN FUNCTIONAL MAPPING OF DOPAMINERGIC PATHWAYS USING PHARMACOLOGICAL MRI
Marion Decrop, Monica van den Berg, Johan Van Audekerke, Ignace Van Spilbeeck, Marleen Verhoye, Daniele Bertoglio
MAPPING THE BRAIN-WIDE NETWORKS UNDERLYING SUSTAINED ATTENTION IN MICE
Arnau Sans Dublanc, Florian Schmidt, Gabriel Montaldo, Olga Symonova, Karl Farrow, Maximilian Joesch
SPREADING DEPRESSION DRIVES REORGANIZATION OF RESTING-STATE PAIN CONNECTIVITY
Bengisu Solgun, Buket Dönmez-Demir, Aslıhan Bahadır-Varol, Hülya Karataş, Şefik Evren Erdener
DISENTANGLING THE MOUSE BRAIN FUNCTIONAL CONNECTOME WITH THE GRAPH THEORY
Grzegorz Olszak, Magdalena Sobien, Aleksandra Petrovskaia, Leszek Kaczmarek, Marzena Stefaniuk, Marcin Baranski
BRAIN STATE SHAPES THE INTRINSIC SENDER-TO-RECEIVER ARCHITECTURE OF THE MOUSE BRAIN
Silvia Gini, Valeria Bedin, Marco Celotto, Loren Kocillari, Davide Todde, Ludovico Coletta, Andrea Luppi, Stefano Panzeri, Alessandro Gozzi
CHARACTERIZING ACC INVOLVEMENT IN EMOTIONAL CONTAGION CIRCUITS USING FUNCTIONAL ULTRASOUND IMAGING IN MICE
Flora Nelissen, Chaoyi Qin, Rick Waasdorp, Ali Lotfi, Turishcheva Polina, Akos Babiczky, Camilo Rojas, Lorenzo De Angelis, David Maresca, Christian Keysers, Baptiste Heiles, Valeria Gazzola