Neuroscience podcasts

Maxim Raginsky joins Paul Middlebrooks to examine brains, AI and biological autonomy through control theory. They discuss what behaviour reveals about a system's internal organisation, analog and digital descriptions, the relationship between control and cybernetics, active inference and the limits of computational accounts. The publisher offers a public episode and supporter access to its full archive.

Hosted by Paul Middlebrooks

Jérémie Naudé and Albert Moukheiber join Alexandra Delbot to examine popular misconceptions about the brain, including claims about dopamine detoxes. They discuss what neuroscience experiments establish about dopamine and reward prediction, and how simplified biological narratives can distort research and public understanding.

Hosted by Alexandra Delbot

Andrew Huberman joins Patrick O’Shaughnessy to discuss the frontier of neurotechnology and sustained human performance. Their conversation considers the convergence of AI and biotechnology, gene-based methods for changing neural activity and motivation, and the relationships between visual behaviour, arousal and sleep. Huberman is a neuroscientist and professor at Stanford University.

Hosted by Patrick O’Shaughnessy

Madeleine Finlay interviews Boston University neuroscientist Steve Ramirez about locating, activating and removing rodent memories, and possible applications in humans.

Hosted by Madeleine Finlay

Francesca and Ilaria discuss taste-receptor research, mitochondrial biology and a reported ALS case study involving an antisense oligonucleotide treatment. Giuliana Galati interviews University of Padua physicist Francesco Recchia about nuclear phenomenology. The episode links these discussions to the underlying research papers and distinguishes a clinical case report from established treatment evidence.

Hosted by Francesca Cecilia Lauta, Ilaria Zanardi

Vincent Racaniello, Alan Dove and Brianne Barker discuss a newly identified mechanism for RNA-guided DNA recognition and genetic control that may predate CRISPR pathways. They also examine research proposing that features of Alzheimer’s disease neuropathology could have originated as a host response to infection in the brain, including evidence concerning phosphorylated tau and herpesvirus activity. The episode connects ancient molecular recognition mechanisms with questions about antiviral defence.

Hosted by Vincent Racaniello, Alan Dove

Neurobiologist Tom Clandinin joins Nicholas Weiler to explore how interacting genetic, cellular and metabolic systems maintain brain health over a lifetime, and how their breakdown contributes to neurodegeneration. The discussion moves beyond single explanations such as inflammation or waste clearance to a systems-level study of brain resilience. Clandinin describes a collaborative programme combining large-scale genetic perturbations in flies and mice with molecular, circuit and behavioural measurements. Computational models will connect these observations across cell types, predict interactions and guide experiments toward potential ways to strengthen the aging brain’s maintenance systems.

Hosted by Nicholas Weiler

Gaute Einevoll and Mihai Petrovici discuss how neuromorphic hardware can support artificial intelligence and efficient brain simulation. They contrast high-frequency arithmetic on conventional silicon with the rich dynamics and millisecond spikes of biological neurons, and explore brain-inspired systems for emulating neural dynamics and studying computation in spiking networks. Petrovici is a senior researcher at the University of Bern. The conversation was recorded on 18 June 2026 and released on 23 September 2026; the publisher’s audio runs 1 hour, 41 minutes and 46 seconds.

Hosted by Gaute Einevoll

Chris Smith presents research on individual differences in fruit flies, colour-linked pupil responses in synaesthesia, and how mating patterns broaden cognitive variation in chickadees. The episode also examines which species succeed in cities and how DNA organisation changes in cancer. The publisher provides a full episode player and individual interview transcripts.

Hosted by Chris Smith

Vincent Racaniello speaks with Roberto Cattaneo and Kalpana Yadav at the 2026 American Society for Virology meeting about measles persistence in the brain. They discuss selection for highly fusogenic viral variants when usual measles receptors are absent, neuron-to-neuron spread, and the development of subacute sclerosing panencephalitis, a rare, fatal delayed complication of measles infection.

Hosted by Vincent Racaniello

Nature staff discuss geophysical evidence that could indicate hidden chambers beyond Tutankhamun's tomb and what the findings might imply for the search for Nefertiti's burial place. The episode also examines a multifunctional brain-computer interface that translates neural activity into both speech and gestures, highlighting how one implant can support several forms of communication.

Neuroscientist George Paxinos speaks with Thanos Chatziandreou about brain mapping, consciousness and the questions that remain open in neuroscience. The Greek-language conversation also considers neurodegenerative disease, prevention, AI and the relationship between scientific knowledge, human behaviour and responsibility for the future.

Hosted by Θάνος Χατζηανδρέου

This Nature Podcast episode examines human brain organoids transplanted into mice lacking a cerebral cortex, where extensive cellular integration could create an in-vivo platform for testing therapies and studying human neurobiology. It also covers research highlights and Paper2Agent, an AI system that turns research papers into interactive virtual corresponding authors able to answer questions and support complex scientific tasks.

The Science Show reviews a new approach to detecting and measuring concussion, a repurposed satellite for mapping the Universe, intervention to conserve a potentially sterile native plant, AI support for people with dyslexia, and how recommendation algorithms influence reading choices.

Hosted by Robyn Williams, Belinda Smith

Carolyn Bertozzi explains why sugars on cell surfaces matter for communication between cells and how new chemical methods make these complex molecules accessible to research. The discussion connects this work to neuroscience, biological aging and drug development.

Hosted by Nicholas Weiler

Cognitive scientist Nafees Hamid discusses research on the motivations of people approaching or already committed to violent extremism. The conversation examines sacred values, social relationships and how psychological research may help disengage people from extremist ideas. The supporting research includes behavioural and neuroimaging studies of willingness to fight and die for a cause. Hosted by Shankar Vedantam. Hidden Brain Media dates this public episode release to 10 September 2026 and provides audio, research references and a transcript. The publisher notes that transcripts can reflect an earlier episode version.

Hosted by Shankar Vedantam

Daniel Levenstein discusses spontaneous activity in the hippocampus and cortex, especially during sleep, and its relationship to learning, memory and navigation. He explains how AI models can help investigate these dynamics, alongside questions about model systems, cognitive maps and the relationship between neuroscience experiments and theory.

Hosted by Paul Middlebrooks

Gaute Einevoll talks with Tatjana Tchumatchenko about a mechanistic mathematical model of how neurons minimize energy use by deciding whether ion-channel proteins are produced locally in dendrites or in the soma. The model’s predictions agree with experimental findings.

Masud Husain explains the neuroscience of motivation, dopamine, effort, and reward, together with research on apathy, dementia, Parkinson's disease, Alzheimer's disease, and cognitive resilience.

Scientific American's Science Quickly examines an early pilot trial of psilocybin-assisted therapy for people with long-term anorexia. The episode carefully discusses reported changes in symptoms and motivation, possible neuroplasticity mechanisms, the small uncontrolled sample and the need for larger randomized studies and clinical safeguards.