Neurochemistry ePosters

Dopamine-dependent cyclic AMP accumulation occurs via activation of D1-like receptors since early development of the chicken retina. Cyclic AMP is an ubiquitous second messenger that regulates several physiological processes including neuronal survival and differentiation. The mTOR pathway is a crucial pathway linking…

Alzheimer’s Disease (AD) is a progressive neurological disorder that gradually deteriorates cognitive abilities and leads to the inability to carry out simple tasks. However, the molecular mechanisms and causes of this disease are still unclear. This research aims to use the proteomic signature of the 5xFAD AD mouse…

Dopamine (DA) neurons in the substantia nigra are vital for the control of movement. This fundamental function is encoded by the output signal of DA neurons which switches from spontaneous firing to bursts of action potentials. The latter produces an increase of DA release in targeted areas which is associated to…

Gangliosides, complex membrane glycosphingolipids, engage in a variety of inter- and intracellular interactions, and play a crucial role in the pathogenesis of various neurological and neurodegenerative diseases. Another membrane constituent, leptin receptor (LepR), modulates feeding behavior by influencing signaling…