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Combined Electrophysiological Optical Recording

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Seminar✓ Recording AvailableNeuroscience

Combined electrophysiological and optical recording of multi-scale neural circuit dynamics

Chris Lewis

University of Zurich

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Monday, April 29, 2024

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Monday, April 29, 2024

3:00 PM Europe/London

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Host: Cambridge NeuroTech

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Cambridge NeuroTech

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Abstract

This webinar will showcase new approaches for electrophysiological recordings using our silicon neural probes and surface arrays combined with diverse optical methods such as wide-field or 2-photon imaging, fiber photometry, and optogenetic perturbations in awake, behaving mice. Multi-modal recording of single units and local field potentials across cortex, hippocampus and thalamus alongside calcium activity via GCaMP6F in cortical neurons in triple-transgenic animals or in hippocampal astrocytes via viral transduction are brought to bear to reveal hitherto inaccessible and under-appreciated aspects of coordinated dynamics in the brain.

Topics

GCaMP6Fastrocytescalcium activitycalcium imagingelectrophysiological recordingselectrophysiologyimaginglocal field potentialsmanipulationmulti-modal recordingoptical methodsoptogenetic perturbationsoptogeneticssilicon neural probestwo-photon imagingwide-field imaging

About the Speaker

Chris Lewis

University of Zurich

Contact & Resources

@cloois

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twitter.com/cloois

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