Engineering human myelination in vitro: Mechanobiologically compatible platforms for CNS drug discovery
UCL Queen Square Institute of Neurology — Department of Neuroinflammation
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Abstract
UCL Department of Neuroinflammation Seminar by Professor Emad Moeendarbary (Professor of Cell Mechanics and Mechanobiology, UCL Mechanical Engineering) on how biophysical factors such as substrate stiffness and axon geometry regulate oligodendrocyte behavior and myelin formation, presenting the AxoMetic in vitro myelination platform for discovery of remyelinating therapies.
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