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Crossing barriers at the axon initial segment

Neuroscience, Molecular Neuroscience and conference by The Royal Society

Edinburgh, United Kingdom
Apex Grassmarket Hotel

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This meeting examines how the axon initial segment controls neuronal firing and polarized transport. The programme connects axo-axonic synapses and human neuronal physiology with cytoskeletal organization, development, disease and activity-dependent plasticity. Approaches include electrophysiology, proteomics, nanoscale and ultrafast imaging, computational modelling and CRISPR perturbation. Discussions consider how ion channels, molecular scaffolds and synaptic inputs jointly regulate excitability.

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