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Memory Formation Hippocampal Microcircuit

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SeminarPast EventNeuroscience

Memory formation in hippocampal microcircuit

Andreakos Nikolaos

Computational Neuroscientist - Early-stage Researcher

Visiting Scientist, School of Computer Science, University of Lincoln, Scientific Associate, National and Kapodistrian University of Athens

Schedule
Thursday, February 6, 2025

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Schedule

Thursday, February 6, 2025

12:00 PM Europe/Athens

Host: Athens Neuroscience

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Athens Neuroscience

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Abstract

The centre of memory is the medial temporal lobe (MTL) and especially the hippocampus. In our research, a more flexible brain-inspired computational microcircuit of the CA1 region of the mammalian hippocampus was upgraded and used to examine how information retrieval could be affected under different conditions. Six models (1-6) were created by modulating different excitatory and inhibitory pathways. The results showed that the increase in the strength of the feedforward excitation was the most effective way to recall memories. In other words, that allows the system to access stored memories more accurately.

Topics

CA1 regioncomputational microcircuitexcitatory pathwaysfeedforward excitationhippocampusinformation retrievalinhibitory pathwaysmedial temporal lobememory formationmemory retrievalneural networks

About the Speaker

Andreakos Nikolaos

Computational Neuroscientist - Early-stage Researcher

Visiting Scientist, School of Computer Science, University of Lincoln, Scientific Associate, National and Kapodistrian University of Athens

Contact & Resources

Personal Website

staff.lincoln.ac.uk/17b5e3be-d68f-45ec-8c39-c2381245d6c8;%20%20https://www.linkedin.com/in/nikolas-andreakos-phd-4711bb155

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