Memory formation in hippocampal microcircuit
Computational Neuroscientist - Early-stage Researcher
Visiting Scientist, School of Computer Science, University of Lincoln, Scientific Associate, National and Kapodistrian University of Athens
Abstract
The centre of memory is the medial temporal lobe (MTL) and especially the hippocampus. In our research, a more flexible brain-inspired computational microcircuit of the CA1 region of the mammalian hippocampus was upgraded and used to examine how information retrieval could be affected under different conditions. Six models (1-6) were created by modulating different excitatory and inhibitory pathways. The results showed that the increase in the strength of the feedforward excitation was the most effective way to recall memories. In other words, that allows the system to access stored memories more accurately.
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