SeminarRecording AvailableOptogenetics

New tools for monitoring and manipulating neural circuits

Monday, February 14, 2022
05:00 UTC
Dr. Loren Looger

HHMI Investigator, Professor Neurosciences, UC San Diego

Recording

Video on demand

Open recording
Hosted by Manitoba Neuroscience Network70 minutes

Abstract

Dr. Looger will present updates on a variety of molecular tools for studying & manipulating neural circuits & other preparations. Topics include genetically encoded calcium indicators (including the new ultra-fast jGCaMP8 variants), neurotransmitter sensors (improved versions for following glutamate, GABA, acetylcholine, serotonin), optogenetic effectors including the new “enhanced Magnets” dimerizers, AAV serotypes for retrograde labeling & altered tropism, probes for correlative light-electron microscopy, chemical gene switches, etc. He will make all his slides freely available - so don’t worry about hurriedly taking notes; instead focus on questions and ideas for collaboration. Please bring your suggestions for molecular tools that would be transformative for the field.

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