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Prof. Dr.
Max Planck Institute for Brain Research
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Schedule
Tuesday, October 27, 2020
3:00 PM Europe/London
Domain
NeuroscienceHost
Cortex Club
Duration
70 minutes
The complex morphology of neurons, with synapses located 100’s of microns from the cell body, necessitates the localization of important cell biological machines and processes within dendrites and axons. Using expansion microscopy together with metabolic labeling we have discovered that both postsynaptic spines and presynaptic terminals exhibit rapid translation, which exhibits differential sensitivity to different neurotransmitters and neuromodulators. In addition, we have explored the unique mechanisms neurons use to meet protein demands at synapses, identifying the transcriptome and translatome in the neuropil.
Erin Schuman
Prof. Dr.
Max Planck Institute for Brain Research
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