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Selectively Silencing Nociceptor Sensory

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SeminarPast EventNeuroscience

Selectively Silencing Nociceptor Sensory Neurons

Clifford J. Woolf

Prof

Harvard Medical School

Schedule
Wednesday, November 17, 2021

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Schedule

Wednesday, November 17, 2021

4:00 PM Europe/London

Host: SONA

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SONA

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Abstract

Local anesthetics decrease the excitability of all neurons by blocking voltage-gated sodium channels non-selectively. We have developed a technology to silence only those sensory neurons – the nociceptors – that trigger pain, itch, and cough. I will tell you why and how we devised the strategy, the way we showed that it works, and will also discuss its implications for treating multiple human disorders.

Topics

coughexcitabilityitchlocal anestheticsneurobiologynociceptorspainsensory neuronssilencing technologyvoltage-gated sodium channels

About the Speaker

Clifford J. Woolf

Prof

Harvard Medical School

Contact & Resources

Personal Website

kirbyneuro.org/WoolfLab/

@SONAorg

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twitter.com/SONAorg

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