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Prof
Biozentrum University of Basel
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Schedule
Monday, November 30, 2020
12:00 PM Europe/Paris
Domain
NeuroscienceHost
ICM Paris Brain Institute
Duration
70 minutes
Neural stem cells reside in the adult mammalian brain. The ventricular-subventricular zone (V-SVZ) gives rise to olfactory bulb neurons, as well as small numbers of glia throughout life. Adult V-SVZ neural stem cells dynamically integrate intrinsic and extrinsic signals to either maintain the quiescent state or to become activated to divide and generate progeny. I will present our recent findings highlighting adult neural stem cell heterogeneity, including the identification of novel gliogenic domains and cell types, and the key roles of physiological state and long-range signals in the regulation of regionally distinct pools of adult neural stem cells.
Fiona Doetsch
Prof
Biozentrum University of Basel
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