Towards resolving the Protein Paradox in longevity and late-life health
Schedule
Monday, September 7, 2020
09:00 UTC
Stephen J. Simpson
Prof.
University of Sydney
Host: Brain-Body Interactions
Recording
Open recording
Event Information
Recording
Available
Host
Brain-Body Interactions
Duration
70 minutes
Abstract
Reducing protein intake (and that of key amino acids) extends lifespan, especially during mid-life and early late-life. Yet, due to a powerful protein appetite, reducing protein in the diet leads to increased food intake, promoting obesity – which shortens lifespan. That is the protein paradox. In the talk I will bring together pieces of the jigsaw, including: specific nutrient appetites, protein leverage, macronutrient interactions on appetite and ageing, the role of branched-chain amino acids and FGF-21, and then I will conclude by showing how these pieces fit together and play out in the modern industrialised food environment to result in the global pandemic of obesity and metabolic disease.
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