Sleep Medicine ePosters

Considering the difficulty in finding a reversible cure for dementia, research and clinical focus have shifted towards modifiable risk factors for cognitive decline, with sleep disturbances gaining attention especially in older adults with mild cognitive impairment (MCI). Given the significant impact of sleep…

Mild traumatic brain injury (mTBI) poses a significant public health concern due to its association with psychiatric complications, including anxiety, depression, and sleep disturbances. Insulin-like growth factor 1 (IGF-1), known for its implications in acromegaly and cancer, has been linked to metabolic syndrome in…

In many neurological disorders, sleep disturbances and intellectual disability are strongly associated.Therefore, by studying these types of disorders, we can attempt to elucidate molecular and cellularmechanisms with broad relevance to brain function and disease. Christianson syndrome (CS) is anexample of a monogenic…

Phenylketonuria (PKU) is a rare, metabolic disease caused by a mutation in the gene for the enzyme phenylalanine hydroxylase (PAH). The resulting enzyme defect reduces the transformation of phenylalanine (Phe) to tyrosine and causes the accumulation of Phe in blood and brain. This elevated Phe concentration obstructs…

Vigilance states are conventionally divided into wake, slow-wave sleep (SWS) and rapid eye-movement (REM) sleep based on distinct patterns of neural activity and muscle tone. These states are traditionally thought to be global. However, there is growing evidence for a departure from a simple model of three basic…

Parkinson's patients face many challenges in their daily lives due to their symptoms. Deep Brain Stimulation (DBS) is an intervention that uses electrical stimulation to help alleviate some of the extrapyramidal symptoms. However, DBS also has some notable side effects, one of which is its impact on sleep. The impact…