Biomedical Engineering
biomedical engineering
Chapman University Brain Institute
We are seeking multiple post-bac research assistants with our projects.
Fabrice Wallois
The main objective of this project is to characterize the endogenous generators underlying the emergence of sensory capacities and to characterize their associated functional connectivity. This will be done retrospectively on our High Resolution EEG database in premature neonates from 24 weeks of gestational age, which is the largest database worldwide. We will also use the OPM pediatric MEG, which is being set up in Amiens. This study will allow us to characterize the establishment of sensory networks before the modulation of cortical activity by external sensory information. The PhD candidate will be concentrated on developing advance signal processing approached using the already available datasets on HR EEG and MEG, for characterization of spontaneous neural oscillations and analysis of functional connectivity.
Sahar Moghimi
The consortium of the projects aims to evaluate the development of rhythm perception starting from the third trimester of gestation into infancy, and the impact of early musical interventions in the NICU on preterm infants’ development. In these cross-sectional and longitudinal studies, we will evaluate the development of auditory rhythm processing capacities with EEG, and behavioral protocols. The project consortium involves four academic partners with complementary expertise in early neurodevelopment, cognitive neurosciences of music, neural data processing (in particular EEG), and music analysis. The aim is to put together a cross-disciplinary team that together covers the following methods: protocol design and implementation, EEG signal processing, behavioral studies, video analysis, statistics, machine learning.
Prof. Alessandro D’Ausilio
The Italian Institute of Technology (Center for Translational Neurophysiology of Speech and Communication - CTNSC) is offering a post-doc position for 1 year (renewable for up to 5Y on secured funds) with a highly competitive salary, in the area of Human Non-Invasive Motor Neurophysiology. The ideal candidate has a PhD in biomedical engineering, neuroscience or experimental psychology with a strong quantitative background. Proven experience in motion capture, EEG or advanced signal processing is highly regarded. The winner, from day-1, will be involved in currently running projects. However, our goal will be to support and guide their smooth transition towards full scientific independence, according to a 5-years plan.
Dr. Stéphane Maison
A NIH-funded postdoctoral position is immediately available in Dr. Stéphane Maison’s laboratory in the Department of Otolaryngology – Head & Neck Surgery at the Massachusetts Eye & Ear – Harvard Medical School. Our research interests focus on identifying biomarkers of a large range of etiologies and their associated disorders including difficulties hearing and communicating in noisy environments, reduced sound level tolerance and tinnitus using a test battery based on behavioral, electrophysiologic, and psychophysical measures. Salary and benefits are consistent with NIH guidelines and institution policies based on applicant’s experience. Highly motivated candidates who recently graduated with a PhD in biomedical engineering, computational biology, hearing science, neuroscience, or other related fields are welcome to apply. The applicant should have strong programming skills (e.g., Matlab, Python), independent and productive. Experience with human testing is preferred but not required. The fellow will receive an appointment at Massachusetts Eye and Ear and Harvard Medical School. Interested applicants should apply using the following link: https://partners.taleo.net/careersection/mee/jobdetail.ftl?job=3299643&tz=GMT-04%3A00&tzname=America%2FNew_York
Stephane Maison
A NIH-funded postdoctoral position is immediately available in the Department of Otolaryngology - Head & Neck Surgery at the Massachusetts Eye & Ear - Harvard Medical School. Salary and benefits are consistent with NIH guidelines and institution policies based on applicant's experience. We are seeking highly motivated candidates who recently graduated with a PhD in hearing science, neuroscience, computer sciences or biomedical engineering. The applicant should have programming skills (e.g., Matlab, Python), be motivated, independent, and productive. Experience with human testing is a plus. The fellow will receive an appointment at Massachusetts Eye and Ear and Harvard Medical School. Our research interests focus on identifying biomarkers of cochlear synaptopathy in patients with a large range of sensorineural etiologies.
Poramate Manoonpong
The School of Information Science and Technology (IST) at Vidyasirimedhi Institute of Science and Technology (VISTEC), Thailand, offers a full-time position (Professor / Associate Professor / Assistant Professor / Lecturer (Tenure Track)). We are expanding our faculty to support the Sense-Think-Act initiative, which focuses on the next generation of AI-driven systems capable of perceiving their environment, reasoning effectively, and acting autonomously. We seek faculty members from diverse fields, including Computer Science, Computer Engineering, Software Engineering, Robotics, and Biomedical Engineering, to drive innovation in AI, robotics, and intelligent systems.
INC Day 2022: Neuroethics
Organized by the INC in partnership with the BioMedical Engineering Paris international Master’s program and the NeuroParis Master’s programs and is supported by the Faculty of Sciences of Paris Cité University and the Graduate school Psychological science.
Measuring the Motions of Mice: Open source tracking with the KineMouse Wheel
Who says you can't reinvent the wheel?! This running wheel for head-fixed mice allows 3D reconstruction of body kinematics using a single camera and DeepLabCut (or similar) software. A lightweight, transparent polycarbonate floor and a mirror mounted on the inside allow two views to be captured simultaneously. All parts are commercially available or laser cut
The wonders and complexities of brain microstructure: Enabling biomedical engineering studies combining imaging and models
Brain microstructure plays a key role in driving the transport of drug molecules directly administered to the brain tissue as in Convection-Enhanced Delivery procedures. This study reports the first systematic attempt to characterize the cytoarchitecture of commissural, long association and projection fiber, namely: the corpus callosum, the fornix and the corona radiata. Ovine samples from three different subjects have been imaged using scanning electron microscope combined with focused ion beam milling. Particular focus has been given to the axons. For each tract, a 3D reconstruction of relatively large volumes (including a significant number of axons) has been performed. Namely, outer axonal ellipticity, outer axonal cross-sectional area and its relative perimeter have been measured. This study [1] provides useful insight into the fibrous organization of the tissue that can be described as composite material presenting elliptical tortuous tubular fibers, leading to a workflow to enable accurate simulations of drug delivery which include well-resolved microstructural features. As a demonstration of the use of these imaging and reconstruction techniques, our research analyses the hydraulic permeability of two white matter (WM) areas (corpus callosum and fornix) whose three-dimensional microstructure was reconstructed starting from the acquisition of the electron microscopy images. Considering that the white matter structure is mainly composed of elongated and parallel axons we computed the permeability along the parallel and perpendicular directions using computational fluid dynamics [2]. The results show a statistically significant difference between parallel and perpendicular permeability, with a ratio about 2 in both the white matter structures analysed, thus demonstrating their anisotropic behaviour. This is in line with the experimental results obtained using perfusion of brain matter [3]. Moreover, we find a significant difference between permeability in corpus callosum and fornix, which suggests that also the white matter heterogeneity should be considered when modelling drug transport in the brain. Our findings, that demonstrate and quantify the anisotropic and heterogeneous character of the white matter, represent a fundamental contribution not only for drug delivery modelling but also for shedding light on the interstitial transport mechanisms in the extracellular space. These and many other discoveries will be discussed during the talk." "1. https://www.researchsquare.com/article/rs-686577/v1, 2. https://www.pnas.org/content/118/36/e2105328118, 3. https://ieeexplore.ieee.org/abstract/document/9198110
Light-degradable hydrogels as dynamic triggers for implantable devices
Triggerable materials capable of being degraded by selective stimuli stand to transform our capacity to precisely control biomedical device activity and performance while reducing the need for invasive interventions. This talk will cover the development of a modular and tunable light-triggerable hydrogel capable of interfacing with implantable devices. We have applied these materials to two applications in the gastrointestinal (GI) tract and demonstrated biocompatibility and on-demand triggering of the material in vitro, ex vivo, and in vivo. Light-triggerable hydrogels have the potential to be applied broadly throughout the GI tract and other anatomic areas. By demonstrating the first use of light-degradable hydrogels in vivo, we provide biomedical engineers and clinicians with a previously unavailable, safe, dynamically deliverable, and precise tool to design dynamically actuated implantable devices.