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Intercellular
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TopicWorld Wide
intercellular communication
Discover seminars, jobs, and research tagged with intercellular communication across World Wide.
2 curated items1 Seminar1 ePoster
Updated about 5 years ago
2 items · intercellular communication
2 results
SeminarNeuroscienceRecording
Virus-like intercellular communication in the nervous system
Jason Shepherd
University of Utah
Nov 16, 2020
The neuronal gene Arc is essential for long-lasting information storage in the mammalian brain and mediates various forms of synaptic plasticity. We recently discovered that Arc self-assembles into virus-like capsids that encapsulate RNA. Endogenous Arc protein is released from neurons in extracellular vesicles that mediate the transfer of Arc mRNA into new target cells. Evolutionary analysis indicates that Arc is derived from a vertebrate lineage of Ty3/gypsy retrotransposons, which are also ancestral to retroviruses such as HIV. These findings suggest that Gag retroelements have been repurposed during evolution to mediate intercellular communication in the nervous system that may underlie cognition and memory.
ePoster
In vivo study of intercellular communication in a glioblastoma mouse model via connexin hemichannels
Viola Donati, Chiara Di Pietro, Chiara Peres, Chiara Nardin, Gina La Sala, Ferdinando Scavizzi, Daniela Marazziti, Marcello Raspa, Fabio Mammano
FENS Forum 2024