Δ9-Tetrahydrocannabinol modulates addictive behaviour induced by saturated and unsaturated high-fat diets in an animal model of operant self-administration
María Roca, Ana Belén Sanz-Martos, Emilio Ambrosio, Nuria Del Olmo · FENS Forum 2024
Obesity has emerged as a prominent global health concern in recent times, a phenomenon often attributed to the excessive consumption of highly palatable, calorie-rich foods laden with sugar and fat. These diets can modulate certain neural pathways, such as the mesolimbic dopaminergic system of reward, but their potential addictive properties are still unknown although its effects have been widely studied. Additionally, Δ9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis sativa, has been found to have an important orexigenic role and modulating properties over the reward
ePoster · Neuroscience