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Topic: activation likelihood estimation

Seminar
1 seminar

In Biology and Brain Imaging

Seminar · Brain Imaging

Meta-analytic evidence of differential prefrontal and early sensory cortex activity during non-social sensory perception in autism

Nazia Jassim · University of Cambridge

Wed, May 19, 2021 · 15:00 UTC

To date, neuroimaging research has had a limited focus on non-social features of autism. As a result, neurobiological explanations for atypical sensory perception in autism are lacking. To address this, we quantitively condensed findings from the non-social autism fMRI literature in line with the current best practices for neuroimaging meta-analyses. Using activation likelihood estimation (ALE), we conducted a series of robust meta-analyses across 83 experiments from 52 fMRI studies investigating differences between autistic (n = 891) and typical (n = 967) participants. We found that typical c