Topic: adipose tissue

Sympathetic nerve activation of adrenergic receptors on fat is the major pathway the brain uses to drive non-shivering thermogenesis in brown adipose tissue and lipolysis in white fat. There is accumulating evidence that the peripheral nerve architecture inside of organs is plastic (can be remodeled) but the factors and conditions that regulate or result in remodeling are largely unknown. Particularly for fat, it remains unclear if nerves in fat can be remodeled in step with hyperplasia/trophy of adipose tissue as result of a prolonged energy surfeit. This talk will discuss our recent work ide

Obesity, a multifaceted condition influenced by various environmental factors, represents a critical public health challenge. Among these factors, dietary choices and exposure to metabolic disrupting compounds (MDCs) play pivotal roles in shaping adipose tissue (AT) functions and its crosstalk with different organs, including the brain. The present collaborative research is integral to the HEAL ITALIA Project (Health Extended Alliance for Innovative Therapies, Advanced Lab-research, and Integrated Approaches of Precision Medicine). Our main objectives are twofold: i) to investigate the impact