Engagement of basal amygdala-nucleus accumbens neurons in the processing of rewarding or aversive social stimuli
Giulia Poggi, Giorgio Bergamini, Redas Dulinskas, Lorraine Madur, Alexandra Greter, Christian Ineichen, Amael Dagostino, Diana Kúkelova, Hannes Sigrist, Klaus Bornemann, Bastian Hengerer, Christopher Pryce · FENS Forum 2024
Basal amygdala (BA)-to-nucleus accumbens (NAc) projection neurons are integral to the circuitry of emotional processing. Recent studies have addressed whether neurons in this population(s) respond to reward, aversion or both emotional valences, but the focus has been on processing of physical emotional stimuli. Here, we extend this to salient social stimuli, whose processing is essential for the whole the animal kingdom and vital for maintaining individual physical and mental health. In male mice, an iterative study was conducted into engagement of BA-NAc neurons in response to social reward (