Topic: cancer immunotherapy

Lead research linking focused ultrasound, synthetic biology and cancer immunotherapy in Nate Yoon’s RPBS Lab. Projects include ultrasound-responsive gene circuits, immune-cell mechanotransduction and acoustic tools for imaging and therapy. Mentor students and develop an independent research trajectory in an interdisciplinary engineering environment. The expected start is 15 January 2027. Applications received by 1 October 2026 receive full consideration; the employer explicitly continues accepting applications until the position is filled.

Jiaqi Zhang examines how computational models can learn the effects of genetic interventions from single-cell experiments. Such experiments reveal causal relationships, but their high-dimensional measurements are costly to collect and difficult to interpret. The seminar connects identifiable causal representations with a predictive method for previously unseen perturbations. The approach incorporates prior biological knowledge and changes in data distributions to estimate responses at individual-cell resolution. It also uses predictions to guide subsequent experiments. An application identifi