CAR T cells

…scientist to develop next-generation CAR T cell therapies for paediatric solid tumours. The work spans molecular and cellular immunotherapy research, including genetic engineering and functional evaluation of CAR T cells and preclinical testing in in vitro and in vivo models. The Mossé programme has focused for more than two decades on the childhood cancer neuroblastoma, with research on genetic susceptibility, somatic mutations and clonal evolution, therapy resistance, immuno-oncology, drug developme

…on developing and refining redirected CAR T cells for malignant brain tumors, including glioblastoma, tumor heterogeneity, immunosuppressive microenvironments, delivery routes, and manufacturing.