Cell segmentation

…Guided R/Bioconductor labs cover cell segmentation, quality control, interactive exploration and integration with single-cell datasets. Downstream analyses characterize cellular niches, neighbourhoods and cell–cell communication. The course concludes with project design and a team hackathon using participant or public data, connecting computational outputs to biological interpretation. 2026-12-14–2026-12-18, 14:00–18:00 daily, Europe/Berlin (CET, UTC+01:00). Online course; fee €530. Designe

Automatically detecting antibody labelled cells within three-dimensional datasets such as whole-brain image stacks generated with light-sheet fluorescence microscopy is a complex task. In this study, we introduce DELiVR, a virtual reality (VR) trained deep learning pipeline for identifying c-Fos+ cells, which serve as markers of neuronal activity, in cleared mouse brains. By employing VR annotation, we significantly accelerated training data generation, resulting in DELiVR surpassing current state-of-the-art methods for cell segmentation. Our pipeline, which encompasses cell detection, brain a