Topic: closed-loop stimulation

This talk presents findings from open and closed-loop neural stimulation experiments using EEG. Fixed-frequency (10 Hz) stimulation revealed cross-cortical alpha power suppression post-stimulation, modulated by the difference between the individual's alpha frequency and the stimulation frequency. Closed-loop stimulation demonstrated phase-dependent effects: trough stimulation enhanced lower alpha activity, while peak stimulation suppressed high alpha to beta activity. These findings provide evidence for homeostatic mechanisms in the brain's response to photic stimulation, with implications for

Sharp-wave ripples (SWRs) are thought to play a crucial role in memory consolidation, learning, and the formation of long-term memories by facilitating the transfer of information from the hippocampus to neocortical networks. To understand the mechanisms governing SWRs, we have developed a closed-loop stimulation framework tailored for the real-time detection and suppression of SWRs, leveraging the ONIX electrophysiology acquisition system and BONSAI-RX acquisition software. As part of our Bonsai package, we developed a convolutional neural network (CNN) for detection of SWRs recorded with lam