ePoster · Electrophysiology
Real-time detection of sharp-wave ripples with a closed-loop stimulation framework
Cem Uran, Carmen Gascó Gálvez, Angela Zordan, Jeroen Bos, Francesco Battaglia, Martin Vinck · Bernstein Conference 2024
Sharp-wave ripples (SWRs) are thought to play a crucial role in memory consolidation, learning, and the formation of long-term memories by facilitating the transfer of information from the hippocampus to neocortical networks. To understand the mechanisms governing SWRs, we have developed a closed-loop stimulation framework tailored for the real-time detection and suppression of SWRs, leveraging the ONIX electrophysiology acquisition system and BONSAI-RX acquisition software. As part of our Bonsai package, we developed a convolutional neural network (CNN) for detection of SWRs recorded with lam