Topic: cortical space

Two-photon holographic optogenetic experiments have revealed that excitatory perturbations induce excitation surrounding the perturbed cell on the order of tens of microns, after which the response is suppressive, forming an inhibitory halo. Here we investigated, through a battery of analytical and inference methods, how the strength and spread of the connections between neurons both in cortical space and in feature (preferred orientation) space define the response of the circuit to few-cells perturbations. First, we obtain two analytical expressions, one exact and the other approximate, for t

To realize goal-directed behavior an executive control mechanism needs to coordinate when and which pieces of working memory (WM) information are operated on in the specific task context. For that, fundamental WM flexibility is desirable so that a given task learned using a specific set of WM items can be immediately performed on novel items too without any extra training (generalization in the spirit of zero-shot learning). Here we apply the computational paradigm of Spatial computing as a candidate mechanism for such generalization in a Delayed Match-To-Sample Task (DMTS), using an attracto