Topic: corticospinal excitability

Understanding how the brain processes motor and tactile imagery is crucial for advancing motor control and rehabilitation.However,there is a knowledge gap in research where EEG recordings are combined with TMS to study the effects of imagery:little is known about tactile imagery (TI) effects.In this study, we aimed to bridge this gap by examining corticospinal excitability during motor imagery (MI) and TI using TMS-EEG.Our previous findings demonstrated that both MI and TI increase corticospinal excitability,with MI having a stronger effect,whereas tactile stimulation (TS) decreases corticospi

We aim to advance the mechanistic understanding of pain anticipation by investigating how the human cortical motor system learns to prepare for aversive somatosensory events. In this study, we tracked how neural oscillations and corticospinal excitability reflect the acquisition and reversal of pain expectations. Using a Pavlovian conditioning task, participants learned to anticipate the occurrence of lateralized aversive shocks. Specifically, during acquisition neutral visual stimuli predicted shocks to either the left (CS+L) or right (CS+R) arm, while another stimulus (CS-) never predicted s

Single-pulse transcranial magnetic stimulation (spTMS) applied to the primary motor cortex (M1) is widely used to assess corticospinal excitability through motor evoked potentials (MEPs). While trial-by-trial variability in MEP amplitude is thought to reflect dynamic shifts in cortical excitability, implications and neural underpinnings of gradual changes in MEP amplitude over the course of a spTMS session remain unexplored. We addressed this gap by investigating the relationship between slow MEP amplitude fluctuations and shifts in electroencephalography (EEG)-derived excitation/inhibition (E

Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that has been widely used in both primary research, as well as clinical treatment of neuropsychiatric disorders. While some previous studies have examined the reliability of single pulse TMS protocols, few have done a systematic evaluation of the influence of pulse shapes and current directions of TMS on test-retest reliability and variability of motor-evoked potential (MEP) measurements.The aim of this study is to investigate the test-retest reliability and variability of MEPs induced by single pulse TMS pro